A molecular staging system for ependymoma
نویسندگان
چکیده
منابع مشابه
Molecular genetics of ependymoma
Brain tumors are the leading cause of cancer death in children, with ependymoma being the third most common and posing a significant clinical burden. Its mechanism of pathogenesis, reliable prognostic indicators, and effective treatments other than surgical resection have all remained elusive. Until recently, ependymoma research was hindered by the small number of tumors available for study, lo...
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Myxopapillary ependymoma (MEPN) generally can be cured by gross total surgical resection and usually manifest a favorable prognosis. However, surgery is less curative in tumors that are large, multifocal or extend outside the thecal sac. Late recurrences may occur, particularly in pediatric patients. The role of adjuvant therapy is unclear in the clinical management of recurrent tumors. Clinica...
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ژورنال
عنوان ژورنال: Nature Reviews Neurology
سال: 2010
ISSN: 1759-4758,1759-4766
DOI: 10.1038/nrneurol.2010.115